GENDER DIFFERENCES IN THE COURSE OF SARS COV-2-19 ACUTE RESPIRATORY VIRAL DISEASE
DOI:
https://doi.org/10.32782/2077-6594.4.1.2021.247013Keywords:
SARS-CoV2-19, women, menAbstract
The aim: to analyze and evaluate the relationship between the course of coronavirus infection and the sex of the patient, the presence of comorbidities and their impact on the course of coronavirus disease.
Materials and methods. We processed 50 case histories of patients admitted to the Regional Clinical Infectious Diseases Hospital of Uzhhorod in December 2020 and January 2021 with a diagnosis of "Other viral pneumonia, 2019 nCoV acute respiratory disease".
Results. Among the patients included in the study group were 26 (52%) women and 24 (48%) men. Of these, the course of moderate disease was observed in 46 patients (93%) and 4 patients (7%) had severe coronavirus infection. 15 patients (30%) out of 50 underwent maintenance oxygen therapy, including non-invasive mechanical ventilation. Among these patients, 6 were women and 9 were men.
Conclusions. Acute respiratory viral disease SARS-CoV2-19 in women and men is basically the same, but there are some differences. For example, in our study, the need to hospitalize women was more common than men. This may be due to the psychology of women and men – women are more likely to see a doctor and monitor their health and well-being more closely.
References
Carol. J. Baker (2019) Coronaviruses, including SARS and MERS. American Academy of Pediatrics – p. 112-114.
Umakanthan S, Sahu P, Ranade AV, Bukelo MM, Rao JS, Abrahao-Machado LF, Dahal S, Kumar H, Kv D. Origin, transmission, diagnosis and management of coronavirus disease 2019 (COVID-19). Postgrad Med J. 2020 Dec;96(1142):753-758. doi: 10.1136/postgradmedj-2020-138234. Epub 2020 Jun 20. PMID: 32563999.
Дані офіційного сайту ВООЗ – WHO official data https://www.euro.who.int/ru/health-topics/health-emergencies/ coronavirus-covid-19.
Zhang XY, Huang HJ, Zhuang DL, Nasser MI, Yang MH, Zhu P, Zhao MY. Biological, clinical and epidemiological features of COVID-19, SARS and MERS and AutoDock simulation of ACE2. Infect Dis Poverty. 2020 Jul 20;9(1):99. doi: 10.1186/s40249-020-00691-6. PMID: 32690096; PMCID: PMC7369569.
Schalk A.F., Hawn M.C. An apparently new respiratory disease of baby chicks. J. Am. Vet. Med. Assoc., 1931, vol. 78, p. 19.
Cavanagh D. A nomenclature for avian coronavirus isolates and the question of species status. Avian Pathol., 2001, vol. 30, no. 2, pp. 109–115. doi: 10.1080/03079450120044506.
Tyrrell D.A., Bynoe M.L. Cultivation of a novel type of common-cold virus in organ cultures. Br. Med. J., 1965, vol. 1, pp. 1467–1470. doi: 10.1136/bmj.1.5448.1467.
В.П. Широбоков Коронавірус та інші емерджентні інфекції Український медичний часопис, 2(1) (136) – III/IV 2020 https://www.umj.com.ua/article/175048/koronavirus-ta-inshi-emerdzhentni-infektsiyi.
Н.А. Беляков, В.В. Рассохин, Е.Б. Ястребова Лекция: Коронавирусная инфекция COVID-19. Часть 1. Природа вируса, патогенез, клинические проявления. https://www.1spbgmu.ru/images/home/covid19.
Single cell RNA sequencing of 13 human tissues identify cell types and receptors of human coronaviruses / F. Qi, S. Qian, S. Zhang, Z. Zhang // Biochemical and Biophysical Research Communications. – 2020. DOI: 10.1016/j.bbrc.2020.03.044.
В.П. Малий, І.М. Асоян, І.В. Сай, І.В. Андрусович Патогенез коронавірусної інфекції COVID-19. Інфекційні хвороби. 2020. 3(101). 73-83.
A. Mitchell, I. Chiwele, J. Costello Coronavirus infection BMJ – BMJ Publishing Group Ltd 2021 Р. 33-36.
