PREDICTION OF OBSTETRIC COMPLICATIONS IN WOMEN WITH NEWLY DISCOVERED HEPATITIS B REPETITIVE ACTIVITY
DOI:
https://doi.org/10.24144/2077-6594.2.2020.201470Keywords:
hepatitis, prognosis, complicationsAbstract
The goal of the work – to trace the course of pregnancy, childbirth, postpartum period in women with newly discovered hepatitis B replicative activity during pregnancy and early neonatal period of their newborns to predict and prevent obstetric complications.
A survey of 43 women who suffered from acute hepatitis B during pregnancy and their newborns and 100 somatically healthy female women and their newborns. All women with newly identified hepatitis B pathogenic activity during pregnancy were divided into two groups: obstetric complications in childbirth and no pathological obstetric changes during the birth act. Based on the analysis of 54 factors, the 12 most significant factors were selected to predict the occurrence of obstetric complications in childbirth, specifically for women with newly diagnosed HS replicative activity during gestation. The probability of obstetric complications is statistically significant (p<0.05) increasing as the degree of risk increases. At the 1st degree of risk the probability of occurrence of obstetric complications does not exceed 21.1%, whereas already at the second stage it reaches 66.7% (p<0.05).
References
Castillo E., Murphy K., Shalkwyk J. Hepatitis B and pregnancy // Journal of Obstetrics and Gynecology Canada. – 2017. – V. 39. – P. 181-190.
Jin J. Screening for Hepatitis B in Pregnant Women // JAMA. 2019;322(4):376. doi:10.1001/jama.2019.9229.
Menzo S., Minosse C., Vincenti D. Long-Term Follow-Up of Acute Hepatitis B: New Insights in Its Natural History and Implications for Antiviral Treatment // Genes (Basel). – 2018. – № 9 (6). – PubMed ID 29895748Р.
Yang L., Wu T., Li J., Xin J. Artificial liver treatment improves survival in patients with hepatitis B-related acute-onchronic liver failure: a case-control matched analysis // Hepatol Res. – 2020. – PubMed ID 3213453.
Zhang X., Ying Y., Zhou P., Liu X. A Stepwise Evaluation of Hepatitis B Virus-Related Acute-on-Chronic Liver Failure to Optimize the Indication for Urgent Liver Transplantation // Dig Dis Sci. – 2020. – PubMed ID 32140946.