CHARACTERISTICS OF LIPID PROFILE IN PATIENTS WITH ARTERIAL HYPERTENSION DEPENDING ON CHRONOTYPE, DAYTIME SLEEPINESS AND DISPOSITIONAL OPTIMISM LEVELS
DOI:
https://doi.org/10.24144/2077-6594.4.1.2022.277083Keywords:
arterial hypertension, cardiometabolic disorders, lipidogram, chronotype, dispositional optimism/pessimism, level of daytime sleepinessAbstract
The aim is to analyze lipidogram indicators, the level of daytime sleepiness, dispositional optimism and chronotype in patients with arterial hypertension in order to establish their relationship. Methods. The study included 42 patients with essential arterial hypertension stage 2, as a component of the metabolic syndrome, who were treated in the therapeutic department of the hospital. Systolic blood pressure (SBP) and diastolic blood pressure (DBP) (in mm Hg) were measured according to a standard protocol. The concentration of lipidogram indicators were determined using commercially available kits on the Cobas 6000 analyzer (Roche Hitachi, Germany), as well as by calculation formulas. Results. Patients with arterial hypertension with an evening chronotype probably have higher values of lipid panel indicators than the group with intermediate and morning chronotypes. Probably higher values of the lipidogram are also found in patients with hypertension with excessive daytime sleepiness compared to the data of patients with absent daytime sleepiness (the concentration of triglycerides is higher by 27.27%, cholesterol-LDL by 33.33%, TG by 118.56%, cholesterol- non-HDL by 49.82% and RH by 118.18%) and in patients with low optimism compared to patients with moderate optimism (TG concentration is higher by 62.00% and RC by 64.44%). Conclusions. According to the obtained results, a deepening of dyslipidemia in patients with arterial hypertension is associated with a shift in the results of questionnaires to a decrease in the level of dispositional optimism, an evening chronotype and excessive daytime sleepiness.
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