The interaction mechanism between cardiac rosette insufficiency and gastric mucosa invagination into the esophagus

Abstract

The purpose of this research is to refine the diagnostic and therapeutic methodologies for gastroesophageal reflux disease (GERD), with a particular focus on the precise assessment of the extent of gastric mucosal intussusception into the esophagus. Materials and methods. The study was conducted through the analysis of 744 video esophagogastroduodenoscopies without sedation at the Kirovograd Regional Hospital of the Kirovograd Regional Council over the period 2023–2024. It employed both quantitative and qualitative analytical techniques to evaluate the endoscopic data and its impact on diseases of the esophagus and stomach. Results. The findings revealed a considerable incidence of cardia mucosa insufficiency and gastric mucosal intussusception. Notably, patients presenting with more significant mucosal intussusception demonstrated greater mucosal defects as per the Los Angeles classification. Moreover, in those with a higher degree of gastric mucosal intussusception into the esophagus, endoscopic evidence of a hiatal hernia was observed. Conclusion. This study has established a direct correlation between the anatomical peculiarities of cardia mucosa insufficiency and gastric mucosal intussusception into the esophagus and the development of gastroesophageal reflux along with related conditions. The results significantly underscore the vital importance of applying metric endoscopic evaluation techniques for the precise diagnosis of GERD and the creation of customized treatment plans for patients. Furthermore, these insights facilitate the exploration of new research avenues in this particular domain, offering promising prospects for future progress and studies.