THE USE OF LOW-POWER VISIBLE SPECTRUM RADIATION AS A NON-MEDICAMENTOUS THERAPEUTIC MEAN (LITERATURE REVIEW)
DOI:
https://doi.org/10.32782/2786-7684/2025-4-18Keywords:
antibiotic resistance, low-power laser radiation, LED radiation, antimicrobial photodynamic therapy, complex therapy, phototherapy, antimicrobial effectAbstract
Introduction. The development of antimicrobial resistance is a natural process and is associated with the ability of microorganisms to neutralize antibacterial drugs, remove them from the cell, modify antibiotic targets, form biofilms, etc. Resistant microorganisms cause increased morbidity and mortality, and significant economic losses. As a result, the urgent task of scientists and practicing physicians is to study the mechanisms of influence of non-drug agents on the microbial cell with the aim of their wider implementation in clinical practice. The purpose of the work is to analyze scientific literature sources on the use of polarized and non-polarized, as well as coherent and non- coherent low-power visible spectrum radiation in the complex therapy of diseases of infectious and non-infectious etiology. Materials and methods. A study and analysis of literature sources was conducted using the PubMed, Google Scholar, and Research Gate search engines. Search keywords: “phototherapy”, “photodynamic therapy”, “antibiotic resistance”, “low-intensity radiation in medicine”. The search depth was 15 years. Results and discussion. Since the discovery of optical quantum devices that generate laser, LED, polarized polychromatic and other types of radiation, a completely new stage in the development of phototherapy has begun. Due to the presence of a number of advantages and the almost complete absence of contraindications, the use of low-intensity radiation of the visible and near-infrared spectrum has found wide application in almost all branches of medicine for the complex therapy of a wide range of pathologies of both infectious and non-infectious etiology. Despite the large number of scientific publications on the mechanism of interaction of low-intensity radiation with biological tissues, many questions, in particular the direct effect of low-power radiation on microbial cells, remain opened. Conclusions. Due to the continuous and irreversible development of antibiotic resistance of microorganisms, the use of non-medicamentous treatments is considered as a supplement and, in some cases, as an alternative to traditional antibiotic therapy. The versatility of the effects of phototherapy and photodynamic therapy, the proven positive effect on biological objects of different levels of organization make this technique one of the most promising therapeutic directions.
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