STRUCTURAL FEATURES OF THE PERICARDIUM IN NORM AND EXPERIMENT: A LITERATURE REVIEW
DOI:
https://doi.org/10.32782/1998-6475.2023.55.22-27Keywords:
pericardium, heart, cardiovascular system, immune system, milky spots, lymphocyteAbstract
Global statistics show a high mortality rate from cardiovascular diseases, which emphasizes the need for a deep understanding of the pericardium and its influence on the functioning of the heart. The heart is separаted from other organs of thoracic cavity by the pericardium, which performs not only structural, but also immune functions. Research into the morphological aspects of the pericardium, particularly its lymphoid component, provides new insights into the role of this organ in maintaining cardiac health. Special attention should be paid to the study of structural changes that occur in the nucleus as a result of experimental influences. It is important to consider not only infectious or traumatic causes, but also autoimmune and metabolic factors that can contribute to the development of inflammation of the pericardium. The article sets itself the task of carrying out a comprehensive analysis of research on the morphofunctional state of the pericardium, in particular in the context of an experiment on rats. Since the anatomy of the rat is similar to the human one, the results of such studies may be promising for solving the problems of cardiovascular pathology in the human body. The use of an integrative approach to the study of the heart allows to reveal not only anatomical and histological aspects, but also to understand the relationship of the heart with the immune system and local homeostasis. Such an approach is necessary for understanding the causes and mechanisms of the development of heart diseases, which determines its importance in the medical and social spheres.
References
ANTONIUK, V.O. (2005) Lektyny ta yikh syrovynni dzherela. PP “Kvart”, Lviv.
BENTKOWSKA, K., HARDGRAVE, A., IQBAL, N., GRESTY, L., MARSDEN, B., MACHARIA, S., JACKSON-JONES, L. (2023) Pericardial and mediastinal fat-associated lymphoid clusters are rapidly activated in an alkane-induced model of systemic lupus erythematosus. Discovery Immunology, 2(1), kyad017.
BERLAND, R., WORTIS, H.H. (2002). Origins and functions of B-1 cells with notes on the role of CD5. Annual Review of Immunology, 20, 253–300.
BILASH, V.P. (2017) Lektynokhimichna kharakterystyka protokovoi systemy pidnyzhnioshchelepnykh slynnykh zaloz liudyny ta deiakykh laboratornykh tvaryn u porivnialnomu aspekti. Bulletin of Vinnytsia National Medical University, 21(1), 231–235.
CHOI, H.S. (2019) The role of innate lymphoid cells in the heart and cardiac inflammation. Ph.D. Thesis, Johns Hopkins University.
DANYLEVYCH, Yu.O., HNATIUK, M.S., KOVALCHUK, M.F. (2012) Sposib modelyuvannya perykardytu. Patent Ukraiiny, 75399.
DUNAYEVSKA, O.F. (2016) Morfometrychni osoblyvosti limfoidnyh vuzlykiv selezinky khrebetnyh tvaryn. Bulletin of the Problems of Biology and Medicine, 4(2), 193–196.
ELEWA, Y.H.A., ICHII, O., KON, Y. (2016) Comparative analysis of mediastinal fat-associated lymphoid cluster development and lung cellular infiltration in murine autoimmune disease models and the corresponding normal control strains. Immunology, 147, 30–40.
ELEWA, Y.H.A., ICHII, O., OTSUKA, S., HASHIMOTO, Y., KON, Y. (2014) Characterization of mouse mediastinal fat-associated lymphoid clusters. Cell and Tissue Research, 357, 731–741.
GANSHINA, I.V. (2016) Serous cavities of coelomic origin as possible organs of the immune system. Biology Bulletin Reviews, 6, 497–504.
GLOBAL BURDEN OF DISEASE (2021) Ischemic heart disease Seattle. Available from: https://www.healthdata.org/results/gbd_summaries/2019/ischemicheart-disease-level-3-cause (accessed 23.12.2023)
GODIN, I.E., GARCIA-PORRERO, J.A., COUTINHO, A., DIETERLEN-LIÈVRE, F., MARCOS, M.A.R. (1993) Para-aortic splanchnopleura from early mouse embryos contains B1a cell progenitors. Nature, 364, 67–70.
HORALSKY, L.P., DUNAYEVSKA, O.F., SOKULSKY, I.M., KOLESNIK, N.L. (2023) Osoblyvosti ontohenezu peryferuchnyh organiv imunnoho zakhystu u sobak. Ukrainian Scientific and Medical Youth Magazine, 138, 105–106.
JACKSON-JONES, L.H., DUNCAN, S.M., MAGALHAES, M.S., CAMPBELL, S.M., MAIZELS, R.M., MCSORLEY, H.J., BÉNÉZECH, C. (2016) Fat-associated lymphoid clusters control local IgM secretion during pleural infection and lung inflammation. Nature Communications, 7(1), 12651.
JANEWAY, C.A., TRAVERS, P., WALPORT, M., SHLOMCHIK, M.J. (2001) Immunobiology: The Immune System in Health and Disease. Garland Science, New York.
KHOMYCH, V.T., MAZURKEVYCH, T.A., DYSHLIUK, N.V., STEHNEY, ZH.G., USENKO, S.I. (2019) Mizhnarodna veterynarna nomenklatura (Terminolohichny slovnyk) [International Veterinary Histological Nomenclature (Terminological Dictionary)]. National University of Life and Environmental Sciences of Ukraine, Kyiv (in Ukrainian).
KRISHNAN, V., STADICK, N., CLARK, R., BAINER, R., VENERIS, J.T., KHAN, SH., DREW, A., RINKER-SCHAEFFER, C. (2012) Using MKK4's metastasis suppressor function to identify and dissect cancer cell-microenvironment interactions during metastatic colonization. Cancer Metastasis Review, 13(3-4), 605-613.
KUPER, C.F., PIETERS, R.H., VAN BILSEN, J.H. (2021) Nanomaterials and the Serosal Immune System in the Thoracic and Peritoneal Cavities. International Journal of Molecular Sciences, 22(5), 2610.
KUPER, C.F., VAN BILSEN, J., WIJNANDS, M.V. (2018) The serosal immune system of the thorax in toxicology. Toxicological Sciences, 164(1), 31–38.
KUSHCH, O.G. (2014) Lektyny v imunomorpholohiyi. World of Medicine and Biology, 4(47), 150–157.
KUSHCH, O.G., ZLOBINA O.V. (2012) Lektynhistokhimichna kharakterystyka limfoyidnoyi tkanyny, asotsiyovanoyi z plodovoyu chastynoyu platsenty, naprykintsi pershoho period vahitnosti u shchuriv. Zaporizhzhia Medical Journal, 3, 89–91.
LESHCHENKO, I.V., LAZARENKO, L.M., PRYBYTKO, I.Yu., FALALEYEVA, T.M., BEREHOVA, T.V. (2015) Antropometrychni pokaznyky u shchuriv za umov, vyklykanoho neonatalnym vvedennyam hlutamatu natriyu, ta profilaktuchno-likuvalnoho vvedennya probiotychnyh shtamiv laktobatsyl ta bifidobakteriy. Bulletin of Problems of Biology and Medicine, 4(2), 180–185.
LUTSYK, M.D., PANASIUK, Ye.N., ANTONIUK, V.A., LUTSYK, A.D., LADNAIA, L.Ya. (1983) Metody issledovaniya uglevodnoy spetsyfichnosti lektinov (metoducheskiye rekomendatsyi), Vysshaya Shkola, Lviv.
MATESHUK-VATSEBA, L.R., HARAPKO, T.V., KYRYK, KH.A., BLYSHCHAK, N.B., PRYMACHENKO, V.I., PIDVALNA, U.YE., BEKESEVYCH, A.M., HRESKO, N.I., LYTVAK, Yu.B., SODOMORA, O.O., SAVKA, I.I., BORYS, R.YA., DZHALILOVA, E.A. (2020) Sposib modeliuvanna eksperymentalnoho alimentarnoho ozhyrinnia oposeredkovanym vplyvom hlutamatu natriiu. Patent Ukrayiny, 144191.
MAURO, A.G., BONAVENTURA, A., VECCHIÉ, A. MEZZAROMA, E., CARBONE, S., NARAYAN, P., POTERE, N., CANNATÀ, A., PAOLINI, J.F., BUSSANI, R., MONTECUCCO, F., SINAGRA, G., VAN TASSEL, B.W., ABBATE, A., TOLDO, S. (2021) The role of NLRP3 inflammasome in pericarditis: potential for therapeutic approaches. Basic to Translational Science, 6(2), 137–150.
MICHAILOVA, K.N., USUNOFF, K.G. (2006) Serosal membranes (Pleura, Pericardium, Peritoneum): normal structure, development and experimental pathology. Springer Science & Business Media, Berlin.
MORI, S., HANNA, P., DACEY, M.J., TEMMA, T., HADAYA, J., ZHU, C., CHANG, G., PEACOCK, W.J., FISHBEIN, M.C., SHIVKUMAR, K. (2022) Comprehensive anatomy of the pericardial space and the sardiac hilum: Anatomical dissections with intact pericardium. JACC: Cardiovascular Imaging, 15(5), 927–942.
NEFIODOV, O.O., BILYSHKO, D.V., KUSHNARIOVA, K.A., SHEVCHENKO, O.S., SHATORNA, V.F., KEFELI-YANOVSKA, O.I., KOZLOVSKA, O.G. (2020) Vyznachennya vplyvu kadmiyu na pokaznyky embriohenezu pry izoliovanomu vvedenni ta v kombinaysiyi z tsytratamy selenu ta hermaniyu. Medical Perspectives, 25(1), 24–31 (in Ukrainian).
NEFIODOVA, O.O., HALPERIN, O.I., SHATORNA, B.F., SHEVCHENKO, I.V., DEMIDENKO, Yu.V., PRYDYUS, I.O., MIASOYID, Yu.P. (2020). Eksperymentalne vyznachennya nakopychennya v sertsi embrioniv soley kadmiyu ta yih vplyvu na emriogenez shchura. Medical Perspectives, 25(3), 8–16.
OIDA, K., NAKAI, T., HAYASHI, T. MIYABO, S., TAKEDA, R. (1984) Plasma lipoproteins of monosodium glutamate-induced obese rats. International Journal of Obesity, 8(5), 385–391.
PANASCO, M.S., PELAJO-MACHADO, M., LENZI, H.L. (2010) Omental and pleural milky spots: different reactivity patterns in mice infected with Schistosoma mansoni reveals coelomic compartmentalisation. Memórias do Instituto Oswaldo Cruz, 105, 440–444.
PARUNGO, C.P., SOYBEL, D.I., COLSON, Y.L., KIM, S.-W., OHNISHI, S., DE GRAND, A.M., LAURENCE, R.G., SOLTESZ, E.G., CHEN, F.Y., COHN, L.H., BAWENDI, MG, FRANGIONI, JV. (2007) Lymphatic drainage of the peritoneal space: a pattern dependent on bowel lymphatics. Annals of Surgical Oncology, 14, 286–298.
PEREZ-SHIBAYAMA, C., LUDEWIG, B. (2015) Tuning up FALCs: Immunological shielding in the body cavities. Nature Immunology, 16, 796–798.
PYKALYUK, V.S., OSMANOV A.Yu. (2011) Philo-, ontohenes organiv i system liudyny. Dolya, Simpheropol.
RANGEL-MORENO, J., MOYRON-QUIROZ, J. E., CARRAGHER, D. M., KUSSER, K., HARTSON, L., MOQUIN, A., RANDALL, T. D. (2009) Omental Milky Spots Develop in the Absence of Lymphoid Tissue-Inducer Cells and Support B and T Cell Responses to Peritoneal Antigens. Immunity, 30, 731–743.
RANVIER, L. (1874) Du developpement et de l’accroissement des vaisseaux sanguins. Archives de Physiologie Normale et Pathologique, 6, 429–449.
SEIRFERT, E. (1923) Studien am Omentum majus des Menschen. Langenbecks. Archiv der Klinischen Chirurgie, 123, 608–683.
SHATORNA, V., LOMYGA, L. (2023) Zminy pokaznykiv embriotoksychnosti khlorydu kadmiyu pry kombinovanomu vvedenni z suktsynatamy tsynku ta midi v khronichnomu eksperymenti na shchurah. Current Problems of Modern Medicine: Bulletin of the Ukrainian Medical Stomatological Academy, 23(4), 247–252.
SIKACHYNA, S.F. (2004) Ranni stadii embrionalnoho rozvytku silskohospodarskyh tvaryn. Dnipro State Agrarian and Economic University, Dnipro.
SILVERSTRE, J.-S. (2021) Modeling Acute Pericarditis: An Inflammatory Step Toward Tailored Therapeutic Strategies. Basic to Translational Science, 6(2), 151–153.
TREUTING, P.M., DINTZIS, S., MONTINE, K.S. (2018) Comparative anatomy and histology: a mouse, rat, and human atlas. Elsevier Inc. Academic Press, Cambridge.
ZERRBINO, D.D., BAGRIYA, M.M., BODNARA, Ya.Ya., DIBROVY, V.A. (2016) Patomorfologia ta histolohia: atlas. Nova Knyha, Vinnytsia.
