THE EFFECT OF COHERENT AND NON-COHERENT RADIATION ON THE GROWTH INTENSITY OF OPPORTUNISTIC MICROORGANISMS
DOI:
https://doi.org/10.32782/1998-6475.2025.59.27Keywords:
antibiotic resistance, opportunistic microorganisms, low-intensity radiation, antimicrobial activityAbstract
Since the introduction of antibacterial drugs into clinical practice, countless human lives have been saved. However, due to the ability of microorganisms to adapt and acquire resistance to antimicrobial agents, there is a noticeable trend of decreasing effectiveness of antibacterial therapy. Despite numerous approaches aimed at solving this problem, the spread of resistant strains shows no signs of slowing down, making antibiotic resistance an unresolved global challenge for humanity. The use of non-pharmacological methods, particularly low-intensity radiation of the visible spectrum, in combating resistant microorganisms offers a number of advantages and is characterized by an almost complete absence of contraindications, making this approach one of the most promising in overcoming antimicrobial resistance. The effect of low-intensity laser radiation and PILER red-spectrum radiation at a power density of 40 mW/cm² on the growth intensity of clinical isolates of Staphylococcus aureus, Candida albicans, Escherichia coli, Klebsiella pneumoniae, and Enterococcus faecalis on solid nutrient media was investigated. It was found that low-intensity laser and PILER radiation have an effect on the growth intensity of the studied strains. The observed effect is dose-dependent: short-term exposures induce stimulation of microbial growth, whereas 20-minute irradiation provides a pronounced antimicrobial effect. The analysis of the antimicrobial activity of low-intensity laser and PILER radiation demonstrated their comparable effectiveness. Considering the proven biostimulatory effect of low-intensity red-spectrum radiation on the human body, low-intensity laser radiation with a wavelength of 660 nm and PILER radiation with a red light filter can be recommended for the complex therapy of a wide range of purulent-inflammatory conditions caused by opportunistic microorganisms.
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