Analysis of artificial intelligence and machine learning models’ effectiveness in regards to bone loss verification as a criterion for assessing the state of periodontal tissues based on orthopantomography data
DOI:
https://doi.org/10.32782/2786-7684/2025-2-7Keywords:
artificial intelligence, machine learning, periodontitis, bone loss, diagnostics, orthopantomograms, radiological examination, oral cavity, periodontium, tooth, assessment criteriaAbstract
Introduction. Artificial intelligence models provide over 70% accuracy in classifying periodontitis cases using datasets of various nature, however, the most significant proportion of such was represented by orthopantomograms.Objective of the research. To analyze data on the effectiveness of using various artificial intelligence and machine learning models for the bone loss verification within the projection of natural teeth as a criterion for assessing the state of periodontal tissues based on orthopantomography data and to establish the accuracy indicators of such models in the structure of comprehensive diagnostics of periodontal patients.Materials and methods. Processing of publications selected for the primary cohort of scientific works was carried out by analyzing their text and providing manual data extraction in accordance with the following research categories: criteria that were used to assess the effectiveness of an artificial intelligence models focused on the detection, quantification and/or classification of the bone loss level in the projection of natural teeth based on orthopantomography data; indicators of the tested models performance effectiveness in accordance with the criteria used in different studies; the technologies (algorithms), which formed the basis for the development of the proposed target artificial intelligence models.Results and discussions. The prevailing part of the studies demonstrated the experience of using convolutional neural networks as the main approach in the structure of artificial intelligence models focused on verifying the level of bone loss in the projection of natural teeth based on the orthopantomography data. According to previously conducted studies cumulative diagnostic accuracy of such networks used for the above-mentioned purpose was equaled to 0,85, while cumulative sensitivity was equaled to 0,84, and cumulative specificity was equaled to 0,85. The processing of orthopantomograms using machine learning models was characterized by high efficiency in verifying cumulative bone loss in the projection of remaining dentition.Conclusions. During the literature review conducted to assess the effectiveness of clinically-oriented artificial intelligence and machine learning models for the verification of bone loss in the projection of remaining dentition, it was found that the accuracy of these models according to previously published studies has increased significantly after 2020, critically approaching the average indicator of 90%, meanwhile some studies demonstrated data controversial to generally established tendencies. Literature data of the 2020–2024 period indicates a pronounced positive growth in the sensitivity indicator of the above-mentioned models, while positive changes in the specificity indicator are less pronounced in terms of dynamics. Convolutional neural networks represent the approach most frequently described in the literature as usable for the development of artificial intelligence models focused on detecting and classifying levels of bone loss in the projection of natural teeth based on the orthopantomography data.
References
Putra RH, Doi C, Yoda N, Astuti ER, Sasaki K. Current applications and development of artificial intelligence for digital dental radiography. Dentomaxillofacial Radiology. 2022 Jan 1;51(1):20210197. https://doi.org/10.1259/dmfr.20210197
Katsumata A. Deep learning and artificial intelligence in dental diagnostic imaging. Japanese Dental Science Review. 2023 Dec 1;59:329-33. https://doi.org/10.1016/j.jdsr.2023.09.004
Revilla-León M, Gómez-Polo M, Barmak AB, Inam W, Kan JY, Kois JC, Akal O. Artificial intelligence models for diagnosing gingivitis and periodontal disease: A systematic review. The Journal of Prosthetic Dentistry. 2023 Dec 1;130(6):816-24. https://doi.org/10.1016/j.prosdent.2022.01.026
Jacobs R, Fontenele RC, Lahoud P, Shujaat S, Bornstein MM. Radiographic diagnosis of periodontal diseases–Current evidence versus innovations. Periodontology 2000. 2024 Jun;95(1):51-69. https://doi.org/10.1111/prd.12580
Lee CT, Kabir T, Nelson J, Sheng S, Meng HW, Van Dyke TE, Walji MF, Jiang X, Shams S. Use of the deep learning approach to measure alveolar bone level. Journal of clinical periodontology. 2022 Mar;49(3):260-9. https://doi.org/10.1111/jcpe.13574
Zhang J, Deng S, Zou T, Jin Z, Jiang S. Artificial intelligence models for periodontitis classification: A systematic review. Journal of Dentistry. 2025 Mar 17:105690. https://doi.org/10.1016/j.jdent.2025.105690
Turosz N, Chęcińska K, Chęciński M, Brzozowska A, Nowak Z, Sikora M. Applications of artificial intelligence in the analysis of dental panoramic radiographs: an overview of systematic reviews. Dentomaxillofacial Radiology. 2023 Oct 1; 52(7):20230284. https://doi.org/10.1259/dmfr.20230284
Fidyawati D, Masulili SL, Iskandar HB, Suhartanto H, Soeroso Y. Artificial Intelligence for Detecting Periodontitis: Systematic Literature Review. The Open Dentistry Journal. 2024 May 2;18(1). https://doi.org/10.2174/0118742106279454240321044427
Polizzi A, Quinzi V, Lo Giudice A, Marzo G, Leonardi R, Isola G. Accuracy of artificial intelligence models in the prediction of periodontitis: a systematic review. JDR Clinical & Translational Research. 2024 Oct;9(4):312-24. https://doi.org/10.1177/23800844241232318
Krois J, Ekert T, Meinhold L, Golla T, Kharbot B, Wittemeier A, Dörfer C, Schwendicke F. Deep learning for the radiographic detection of periodontal bone loss. Scientific reports. 2019 Jun 11;9(1):8495. https://doi.org/10.1038/s41598-019-44839-3
Kim J, Lee HS, Song IS, Jung KH. DeNTNet: Deep Neural Transfer Network for the detection of periodontal bone loss using panoramic dental radiographs. Scientific reports. 2019 Nov 26;9(1):17615. https://doi.org/10.1038/s41598-019-53758-2
Chang HJ, Lee SJ, Yong TH, Shin NY, Jang BG, Kim JE, Huh KH, Lee SS, Heo MS, Choi SC, Kim TI. Deep learning hybrid method to automatically diagnose periodontal bone loss and stage periodontitis. Scientific reports. 2020 May 5;10(1):7531. https://doi.org/10.1038/s41598-020-64509-z
Kurt S, Çelik Ö, Bayrakdar İŞ, Orhan K, Bilgir E, Odabas A, Aslan AF. Success of aartificial intelligence system in determining alveolar bone loss from dental panoramic radiography images. Cumhuriyet Dental Journal. 2020 Dec 31; 23(4):318-24. https://doi.org/10.7126/cumudj.777057
Sunnetci KM, Ulukaya S, Alkan A. Periodontal bone loss detection based on hybrid deep learning and machine learning models with a user-friendly application. Biomedical Signal Processing and Control. 2022 Aug 1;77:103844. https://doi.org/10.1016/j.bspc.2022.103844
Zadrożny Ł, Regulski P, Brus-Sawczuk K, Czajkowska M, Parkanyi L, Ganz S, Mijiritsky E. Artificial intelligence application in assessment of panoramic radiographs. Diagnostics. 2022 Jan 17;12(1):224. https://doi.org/10.3390/diagnostics12010224
Amasya H, Jaju PP, Ezhov M, Gusarev M, Atakan C, Sanders A, Manulius D, Golitskya M, Shrivastava K, Singh A, Gupta A. Development and validation of an artificial intelligence software for periodontal bone loss in panoramic imaging. International Journal of Imaging Systems and Technology. 2024 Jan;34(1):e22973. https://doi.org/10.1002/ima.22973
Kurt-Bayrakdar S, Bayrakdar İŞ, Yavuz MB, Sali N, Çelik Ö, Köse O, Uzun Saylan BC, Kuleli B, Jagtap R, Orhan K. Detection of periodontal bone loss patterns and furcation defects from panoramic radiographs using deep learning algorithm: a retrospective study. BMC Oral Health. 2024 Jan 31;24(1):155. https://doi.org/10.1186/s12903-024-03896-5
Cerda Mardini D, Cerda Mardini P, Vicuña Iturriaga DP, Ortuño Borroto DR. Determining the efficacy of a machine learning model for measuring periodontal bone loss. BMC Oral Health. 2024 Jan 17;24(1):100. https://doi.org/10.1186/s12903-023-03819-w
Tariq A, Nakhi FB, Salah F, Eltayeb G, Abdulla GJ, Najim N, Khedr SA, Elkerdasy S, Al-Rawi N, Alkawas S, Mohammed M. Efficiency and accuracy of artificial intelligence in the radiographic detection of periodontal bone loss: A systematic review. Imaging Science in Dentistry. 2023 Aug 2;53(3):193. https://doi.org/10.5624/isd.20230092
Ferrara E, Rapone B, D’Albenzio A. Applications of deep learning in periodontal disease diagnosis and management: a systematic review and critical appraisal. Journal of Medical Artificial Intelligence. 2025 Sep 30;8. https://doi.org/10.21037/jmai-24-241
Khubrani YH, Thomas D, Slator PJ, White RD, Farnell DJ. Detection of periodontal bone loss and periodontitis from 2D dental radiographs via machine learning and deep learning: systematic review employing APPRAISE-AI and meta-analysis. Dentomaxillofacial Radiology. 2025 Feb;54(2):89-108. https://doi.org/10.1093/dmfr/twae070
Chawla K, Garg V. Accuracy of convolutional neural network in the diagnosis of alveolar bone loss due to periodontal disease: A systematic review and meta-analysis. Journal of Datta Meghe Institute of Medical Sciences University. 2023 Jan 1; 18(1):163-72. https://doi.org/10.4103/jdmimsu.jdmimsu_281_22
Xue T, Chen L, Sun Q. Deep learning method to automatically diagnose periodontal bone loss and periodontitis stage in dental panoramic radiograph. Journal of Dentistry. 2024 Nov 1;150:105373. https://doi.org/10.1016/j.jdent.2024.105373
Ryu J, Lee DM, Jung YH, Kwon O, Park S, Hwang J, Lee JY. Automated detection of periodontal bone loss using deep learning and panoramic radiographs: a convolutional neural network approach. Applied Sciences. 2023 Apr 23;13(9):5261. https://doi.org/10.3390/app13095261
Sheryl Abraham T, Jeyakumar V, Marthi Krishna Kumar G, Abraham Anandapandian P. Automated Analysis of Tooth Anatomy and Pathological Conditions from Orthopantomogram using Deep Neural Networks. IETE Journal of Research. 2024 Dec 1; 70(12):8702-13. https://doi.org/10.1080/03772063.2024.2385044
Chen CC, Wu YF, Aung LM, Lin JC, Ngo ST, Su JN, Lin YM, Chang WJ. Automatic recognition of teeth and periodontal bone loss measurement in digital radiographs using deep-learning artificial intelligence. Journal of dental sciences. 2023 Jul 1; 18(3):1301-9. https://doi.org/10.1016/j.jds.2023.03.020